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Megha Nagaswami
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Department of Psychology

University of California, Los Angeles



A Patient With Electroconvulsive Therapy–resistant Major Depressive Disorder With a Full Response to Heated Yoga: A Case Report


Journal article


H. Sakurai, Richard Norton, Lauren B. Fisher, Megha Nagaswami, C. Streeter, Ashley K Meyer, Taquesha Dean, M. Fava, D. Mischoulon, M. Nyer
Journal of Psychiatric Practice, 2021

Semantic Scholar DOI PubMed
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APA   Click to copy
Sakurai, H., Norton, R., Fisher, L. B., Nagaswami, M., Streeter, C., Meyer, A. K., … Nyer, M. (2021). A Patient With Electroconvulsive Therapy–resistant Major Depressive Disorder With a Full Response to Heated Yoga: A Case Report. Journal of Psychiatric Practice.


Chicago/Turabian   Click to copy
Sakurai, H., Richard Norton, Lauren B. Fisher, Megha Nagaswami, C. Streeter, Ashley K Meyer, Taquesha Dean, M. Fava, D. Mischoulon, and M. Nyer. “A Patient With Electroconvulsive Therapy–Resistant Major Depressive Disorder With a Full Response to Heated Yoga: A Case Report.” Journal of Psychiatric Practice (2021).


MLA   Click to copy
Sakurai, H., et al. “A Patient With Electroconvulsive Therapy–Resistant Major Depressive Disorder With a Full Response to Heated Yoga: A Case Report.” Journal of Psychiatric Practice, 2021.


BibTeX   Click to copy

@article{h2021a,
  title = {A Patient With Electroconvulsive Therapy–resistant Major Depressive Disorder With a Full Response to Heated Yoga: A Case Report},
  year = {2021},
  journal = {Journal of Psychiatric Practice},
  author = {Sakurai, H. and Norton, Richard and Fisher, Lauren B. and Nagaswami, Megha and Streeter, C. and Meyer, Ashley K and Dean, Taquesha and Fava, M. and Mischoulon, D. and Nyer, M.}
}

Abstract

Supplemental Digital Content is available in the text. Depression remains difficult to treat as a result of less than optimal efficacy and troublesome side effects of antidepressants. The authors present the case of a patient with treatment-resistant depression with melancholic features who had previously been unresponsive to electroconvulsive therapy (ECT) plus an antidepressant regimen but whose condition fully remitted with the addition of a standardized form of heated hatha yoga (HY; Bikram yoga) practiced in a room heated to 105°F. The patient was a 28-year-old woman who underwent 8 weeks of HY as part of a randomized controlled trial of HY for depression while continuing her antidepressant treatment. The patient was asked to attend a minimum of 2 weekly, 90-minute HY classes. After 8 weeks (12 classes in total), the patient no longer met the criteria for a major depressive episode with melancholic features, per Mini-International Neuropsychiatric Interview (MINI) criteria. Her depressive symptoms had improved dramatically, with Inventory of Depressive Symptomatology, Clinician-Rated (IDS-C30), and Hamilton Depression Rating Scale (HAM-D28) scores decreasing from 28 at baseline to 3, and from 28 at baseline to 4, respectively, indicating remission. This patient’s ECT-resistant depression remitted with the addition of HY to her antidepressant regimen. Because of her youth and athleticism, this patient was likely well suited to this rigorous form of yoga. Further research is needed to explore HY as a potential intervention for treatment-resistant depression.


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